Relationship Between Coping Strategies and Quality of Life with Mediating Role of Depression and Stigmatization among Patients with Opioid Use Disorder (OUD) With Relapse Condition

Abstract

The current study aims to investigate the relationship between coping strategies and quality of life (QOL) with the mediating role of depression and stigma among patients with opioid use disorder (OUD). In this correlational study, a total sample of 357 participants was taken from different hospitals and rehabilitation centers. The patients (20 to 65 years) who have a history of relapse at least once a time were included. with relapse condition. Demographic form, Patient Health Questionnaire-9 (PHQ-9), Brief Coping Inventory (BCI), WHO-Quality of Life Scale (WHO-QLS), and Perceived Stigma Scale were used. All the data were scrutinized, and the final data was assessed using SPSS version-26. The findings showed that the direct effect of coping strategies was a significant negative predictor of depression and stigma among patients with opioid use disorder-relapse conditions. Depression and stigma were found to be significant negative predictors of quality of life. Furthermore, the findings reveal that depression and stigma play significant mediating between coping and quality of life among patients with opioid use disorder-relapse condition. It is concluded that coping is a significant predictor of QOL and depression and stigma play significant mediating roles in the increase and decrease of the QOL among patients with OUD.